Archeron

May 10, 2020

Response to Copper Stress in Streptomyces lividans Extends

A copper-sensitive operon repressor protein (CsoR) has been identified in Streptomyces lividans (CsoRSl) and found to regulate copper homeostasis with attomolar affinity for Cu(I). Solution studies reveal apo- and CuI -CsoRSl to be a tetramer assembly, and a 1.7-A˚ resolution crystal structure of apo-CsoRSl reveals that a significant conformational change is necessary to enable Cu(I) binding.
May 10, 2020

Modulating the Cascade architecture of a minimal

Shewanella putrefaciens CN-32 contains a single Type I-Fv CRISPR-Cas system which confers adaptive immunity against bacteriophage infection. Three Cas proteins (Cas6f, Cas7fv, Cas5fv) and mature CRISPR RNAs were shown to be required for the assembly of an interference complex termed Cascade.
May 10, 2020

Interference activity of a minimal Type-I CRISPR Cas

Type I CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)–Cas (CRISPRassociated) systems exist in bacterial and archaeal organisms and provide immunity against foreign DNA. The Cas protein content of the DNA interference complexes (termed Cascade) varies between different CRISPR-Cas subtypes.
May 10, 2020

Quantum Radar Archeron Group

The working principle of a Quantum Radar (QR) is based on the principle of Quantum Illumination (QI) which in turn has at its heart the phenomenon of Quantum Entanglement of continuous variables. Similar to the discrete case, variables having continuum outcomes may as well be entangled.