Interference activity of a minimal Type-I CRISPR Cas

Interference activity of a minimal Type-I CRISPR Cas

Type I CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)–Cas (CRISPRassociated) systems exist in bacterial and archaeal organisms and provide immunity against foreign DNA. The Cas protein content of the DNA interference complexes (termed Cascade) varies between different CRISPR-Cas subtypes.

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